DEAR DR. ROACH: I see information and research for men with hormone issues (testosterone) and resulting problems with impotence, etc. I have not seen any interest in clinical testing for women who are refused hormone replacement therapy due to past breast cancer (and, in my case, also a complete hysterectomy ).

Not only has my desire for physical intimacy completely disappeared, but the hot flashes and sweating are out of control — that is to say, 24/7. I experience depression and lack of energy, as well as lack of interest in traveling or things that usually attract me.

My situation is not unique. Can you help with some solution? — Anon.

ANSWER: Women with a personal history of breast cancer almost always are advised against taking hormone replacement therapy. Despite some trials that did not show clear harm, I cannot recommend estrogen via pill or patch.

You are describing some common symptoms of postmenopausal women, including low libido and hot flashes. Depressive symptoms, including feeling down, a lack of energy and loss of interest, also are more common in women around menopause.

There are nonpharmacologic options for libido, hot flashes and depressive symptoms. However, there are also pharmacologic treatments. For low libido, testosterone therapy sometimes is used.

A new drug, flibanserin, is very modestly successful. It is indicated only in premenopausal women, but one well-done study showed that postmenopausal women had similar results and side effects.

For hot flashes, nonhormonal treatment, such as venlafaxine or paroxetine, is effective. As these are antidepressants, they may be effective against your symptoms of depression, lack of energy and lack of interest in things you used to enjoy.

A careful provider, listening to all of your symptoms, will try to find a course of action.

DEAR DR. ROACH: I have been fighting dry mouth for six years now. I have seen two dentists and five doctors, and they all seem to shy away from my problem.

My mouth is dry all over, and on the left side, my mouth gets raw. What is the problem? — M.M.

ANSWER: Severe dry mouth is not a common problem, but it is important — unless it is treated promptly, it is associated with rapid tooth decay and loss. I see severe dry mouth most commonly with Sjogren’s syndrome — an inflammatory disorder where salivary glands are damaged by the inflammatory response — and in people with head and neck cancer who have undergone surgery and radiation. However, dry mouth also can be related to medications or other diseases.

Treatment for dry mouth has to be individualized. All people with this problem need a dentist with experience treating people with dry mouth.


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Dr. Roach regrets that he is unable to answer individual letters, but will incorporate them in the column whenever possible. Readers may email questions to ToYourGoodHealth@med.cornell.eduor request an order form of available health newsletters at 628 Virginia Dr., Orlando, FL 32803. Health newsletters may be ordered from www.rbmamall.com