For the second game in a row, the Arizona Wildcats are one-score underdogs.
Arizona opens as a 7.5-point underdog for its Big 12 opener against the 12th-ranked Iowa State Cyclones in Ames on Saturday, according to Action Network.
The over/under for Arizona-Iowa State is 49.5 points.
Arizona’s Big 12 opener against No. 12 Iowa State will kick off at 4 p.m. on Sept. 27 at Jack Trice Stadium in Ames, Iowa on ESPN. Arizona and Iowa State are both coming off bye weeks.
Arizona (3-0) is off to its best start in a decade after wins over Hawaii, Weber State and Kansas State. The 12th-ranked Cyclones (4-0) are currently the highest-ranked team in the Big 12, with wins over Kansas State, South Dakota, Iowa and Arkansas State.
The matchup between Arizona and Iowa State will be the seventh contest between the Wildcats and Cyclones dating back to 1948. Arizona is 4-1-1 all-time against Iowa State. Arizona won the last matchup, 21-12, in Ames in 1968.
