The NFL Week 17 slate begins on Thursday, Dec. 28 and concludes on New Year’s Eve with a full slate of Sunday action that includes several matchups that will be key to teams’ postseason hopes.

Below are early Week 17 NFL odds for all games plus betting previews for the biggest games on the schedule.

2023 NFL Week 17 odds: Spread, moneyline favorite on every Week 17 NFL game

Week 17 Early NFL odds: Detroit at Dallas (-5.5, -238) - Saturday, 8:15 p.m. ET

The Lions are riding high after securing their first division title since 1993 with a hard-fought win over the Vikings, and at 11-4, remain very much in play for the NFC’s top seed.

The Cowboys’ last-second loss to the Dolphins leaves them hoping the Eagles can somehow stumble a fourth straight week Christmas Day against the Giants.

Week 17 NFL betting lines: Miami at Baltimore (-3, -156) - Sunday, 1:00 p.m. ET

The Dolphins got the job done against a tough Cowboys squad Christmas Eve and now get a second straight stringent test against the team they’re chasing for the No.1 seed.

The Ravens head into their Christmas Night showdown with the Niners a half-game up on Miami in the AFC, but a loss to San Fran would leave them tied at 11-4 with their Week 17 visitors.

Best NFL odds Week 17: New Orleans at Tampa Bay (-3, -162) - Sunday, 1:00 p.m. ET

The NFC South remains up for grabs, but the Saints will need a win to preserve their hopes. New Orleans will have to hope it can leverage its rest advantage in this tough spot.

The Buccaneers’ impressive Week 16 win against the Jags was their fourth straight. At 8-7 and with a one-game lead in the division, the Bucs simply need to win their last two to lock in their postseason ticket.

Green Bay at Minnesota (-2, -126) - Sunday, 8:20 p.m. ET

The Pack nearly blew a critical game against the Panthers in Week 16 and were unusually generous in pass defense.

The Vikings did suffer a high-scoring loss and saw both Jordan Addison and T.J. Hockenson go down with injuries, clouding the outlook for the offense heading into Week 17 prep.

Early NFL Odds Week 17

  • New York Jets at Cleveland (-6.5) - 8:15 p.m. ET, Thursday, 12/28
  • Tennessee at Houston (-4.5) - 1 p.m. ET
  • Las Vegas at Indianapolis (-3.5) -1 p.m. ET
  • New England at Buffalo (-13.5) - 1 p.m. ET
  • Arizona at Philadelphia (-11.5) - 1 p.m. ET
  • Atlanta at Chicago (-3) - 1 p.m. ET
  • San Francisco (-13.5) at Washington - 1 p.m. ET
  • Los Angeles Rams (-6.5) at New York Giants - 1 p.m. ET
  • Carolina at Jacksonville (-9) - 1 p.m. ET
  • Pittsburgh at Seattle (-3.5) - 4:05 p.m. ET
  • Cincinnati at Kansas City (-7.5) - 4:25 p.m. ET
  • Los Angeles Chargers at Denver (-6.5) - 4:25 p.m. ET

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Juan Carlos Blanco is a Catena Media contributor and has been writing about sports betting and fantasy sports since 2015 for a wide variety of industry websites, and his work has also been syndicated in outlets such as Yahoo Sports, CBS Sports and NBA.com. Follow his work via Twitter @jcblanco22.