Just when it appeared Josh Allen and the Buffalo Bills would celebrate his 12th fourth-quarter game-winning drive, Kyler Murray and the Arizona Cardinals had other ideas.
DeAndre Hopkins caught a 43-yard-pass in between three Bills defenders with two seconds left to give the Arizona Cardinals a miraculous 32-30 victory over the Bills on Sunday.
KYLER MURRAY HAIL MARY TO DEANDRE HOPKINS🚀 pic.twitter.com/z4aThLrN3p
— PFF (@PFF) November 16, 2020
Murray scrambled to his left an eluded a Bills tackler before turning and throwing to a leaping Hopkins, who finished with seven receptions for 127 yards.
The Bills seemed to have victory in hand after Allen found a diving Stefon Diggs in the corner of the end zone with 34 seconds remaining for a 21-yard touchdown that capped a 12-play drive that went 38 yards.
Murray found Isabella for a 14-yard gain as the Cardinals started the final drive at their 25-yard line. He then found Hopkins for nine yards and Larry Ftizgerald for nine yards before the touchdown throw.
Murray finished 22 for 32 for 245 yards, one touchdown and and an interception.
Allen was 32 for 49 for 284 yards and two touchdowns. He had two costly interceptions in the second half and could have thrown two others in the first half.
The Bills led 23-9 after Cole Beasley's 22-yard touchdown with 9:58 remaining in the third quarter, but Arizona scored 17 unanswered points to take a 26-23 lead.
Buffalo dropped to 7-3 and must sit on the heartbreaking loss as they head to the bye week.




