Are upsets on the menu this week in the Big 12 Conference?

No. 11 BYU and No. 24 Arizona State could be vulnerable to the dreaded "letdown game" after registering emotional, field-storming victories last week.

The Cougars visit Iowa State, which is coming off a bye. The Sun Devils host 6-1 Houston and won't have the services of star receiver Jordyn Tyson (hamstring).

Although Arizona has a bye this week, our staff prognosticators, Michael Lev and Justin Spears, do not. They're back to pick every game on this week's slate straight up and against the spread. Lev and Spears are joined this season by Jordan Hamm of Sports360AZ.com.

For more on our predictions — plus a state-of-the-union assessment of the Wildcats — check out The Wildcast. It’s available on AppleSpotify or wherever you get your podcasts.

BYU quarterback Bear Bachmeier (47) celebrates with fans after beating Utah 24-21 on Saturday, Oct. 18, 2025, in Provo, Utah.

SATURDAY, Oct. 25

Matchup: Kansas State (+2.5) at Kansas

Time/TV: 9 a.m., TNT

Hamm's prediction: Kansas to win and cover

Lev’s prediction: Kansas to win and cover

Spears’ prediction: Kansas to win and cover

Matchup: No. 11 BYU (+3.5) at Iowa State 

Time/TV: 12:30 p.m., FOX/11

Hamm's prediction: Iowa State to win and cover

Lev’s prediction: Iowa State to win and cover

Spears’ prediction: Iowa State to win and cover

Matchup: Oklahoma State (+38.5) at No. 14 Texas Tech

Time/TV: 1 p.m., ESPNU

Hamm's prediction: Texas Tech to win, OSU to cover

Lev’s prediction: Texas Tech to win and cover 

Spears’ prediction: Texas Tech to win and cover  

Matchup: Baylor (+4.5) at No. 21 Cincinnati

Time/TV: 1 p.m., ESPN2

Hamm's prediction: Baylor to win outright

Lev’s prediction: Cincinnati to win, Baylor to cover

Spears’ prediction: Cincinnati to win and cover

Matchup: TCU (-15.5) at West Virginia

Time/TV: 3 p.m., ESPN+

Hamm's prediction: TCU to win and cover

Arizona State defends Texas Tech's last-play Hail Mary attempt to complete its upset of the Red Raiders on Saturday, Oct. 18, 2025, in Tempe.

Lev’s prediction: TCU to win and cover

Spears’ prediction: TCU to win, West Virginia to cover

Matchup: Houston (+7.5) at No. 24 Arizona State

Time/TV: 5 p.m., ESPN2

Hamm's prediction: ASU to win, Houston to cover

Lev’s prediction: ASU to win, Houston to cover

Spears’ prediction: ASU to win, Houston to cover

Matchup: Colorado (+13.5) at Utah

Time/TV: 7:15 p.m., ESPN

Hamm's prediction: Utah to win and cover

Lev’s prediction: Utah to win, Colorado to cover

Spears’ prediction: Utah to win, Colorado to cover 

LAST WEEK'S RECORDS

Hamm: 3-3 straight up, 3-3 against the spread

Lev: 2-4 SU, 1-5 ATS

Spears: 3-3 SU, 1-5 ATS

SEASON TO DATE

Hamm: 41-18 SU, 29-30 ATS

Lev: 40-19 SU, 26-33 ATS

Spears: 42-17 SU, 30-29 ATS


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Contact sports reporter/columnist Michael Lev at mlev@tucson.com. On X (Twitter): @michaeljlev. On Bluesky: @michaeljlev.bsky.social