We're getting a sneak preview of conference play in the Big 12 this week.
Colorado and Houston are playing an official league game on Friday.
Arizona and Kansas State are playing an unofficial one.
Those two contests lead off another packed slate of Big 12 football.
Our staff prognosticators, Michael Lev and Justin Spears, are back to pick the top seven games of the week straight up and against the spread. Lev and Spears are joined this season by Jordan Hamm of Sports360AZ.com.
For more on our predictions — plus a complete breakdown of the UA-KSU matchup at Arizona Stadium — check out The Wildcast podcast. It’s available on Apple, Spotify or wherever you get your podcasts.
FRIDAY, Sept. 12
Arizona wide receiver Javin Whatley (6) gets a hand from some fans for his long-bomb touchdown against Weber State in the first quarter, Sept. 6, 2025, at Arizona Stadium.
Matchup: Colorado (+5.5) at Houston
Time/TV: 4:30 p.m., ESPN
Hamm's prediction: Houston to win and cover
Lev’s prediction: Houston to win and cover
Spears’ prediction: Houston to win and cover
Matchup: Kansas State (-1.5) at Arizona
Time/TV: 6 p.m., FOX/11
Hamm's prediction: Arizona to win outright
Lev’s prediction: Kansas State to win and cover
Spears’ prediction: Arizona to win outright
SATURDAY, Sept. 13
Matchup: Pittsburgh (-6.5) at West Virginia
West Virginia head coach Rich Rodriguez listens to a question during Big 12 football media days in Frisco, Texas, July 9, 2025.
Time/TV: 12:30 p.m., ESPN
Hamm's prediction: Pittsburgh to win, West Virginia to cover
Lev’s prediction: Pittsburgh to win and cover
Spears’ prediction: Pittsburgh to win and cover
Matchup: Oregon State (+24.5) at Texas Tech
Time/TV: 12:30 p.m., FOX/11
Hamm's prediction: Texas Tech to win, Oregon State to cover
Lev’s prediction: Texas Tech to win, Oregon State to cover
Spears’ prediction: Texas Tech to win, Oregon State to cover
Matchup: Iowa State (-20.5) at Arkansas State
Time/TV: 1 p.m., ESPN2
Iowa State quarterback Rocco Becht (3) signals teammates during the first half of the Cyclones' game against Iowa, Sept. 6, 2025, in Ames, Iowa.
Hamm's prediction: Iowa State to win, Arkansas State to cover
Lev’s prediction: Iowa State to win, Arkansas State to cover
Spears’ prediction: Iowa State to win and cover
Matchup: Utah (-23.5) at Wyoming
Time/TV: 5 p.m., CBS Sports Network
Hamm's prediction: Utah to win and cover
Lev’s prediction: Utah to win, Wyoming to cover
Spears’ prediction: Utah to win, Wyoming to cover
Matchup: Texas State (+15.5) at Arizona State
Time/TV: 7:30 p.m., TNT
Hamm's prediction: ASU to win and cover
Lev’s prediction: ASU to win and cover
Spears’ prediction: ASU to win and cover
LAST WEEK'S RECORDS
Hamm: 4-4 straight up, 4-4 against the spread
Lev:4-4 SU, 6-2 ATS
Spears: 4-4 SU, 4-4 ATS
SEASON TO DATE
Hamm: 10-6 SU, 8-8 ATS
Lev: 11-5 SU, 10-6 ATS
Spears: 10-6 SU, 10-6 ATS
