Unlike Week 1, this week's college football slate is devoid of Top 10 matchups.
But the Big 12 slate is loaded with intriguing games.
Can Baylor avoid an 0-2 start vs. No. 17 SMU?
Can Iowa State keep the Cy-Hawk Trophy?
Who will win the renewal of the "Border Showdown"?
Can Arizona State avoid the fate that befell Arizona at Mississippi State in 2023?
The UA doesn't have a marquee matchup this week, hosting FCS Weber State. But it's an important next step for the Tucson Wildcats before Kansas State comes to town next week.
Our staff prognosticators, Michael Lev and Justin Spears, are back to pick the top eight games of the week straight up and against the spread. Lev and Spears are joined this season by Jordan Hamm of Sports360AZ.com.
For more on our predictions — plus a complete breakdown of the Arizona-Weber State matchup Saturday night — check out The Wildcast podcast. It’s available on Apple, Spotify or wherever you get your podcasts.
Stickers showing the number 95 in honor of former teammate Alex Foster, killed in May in Mississippi, and a Texas decal with a green ribbon honoring the victims of the Kerrville, Texas, flooding are seen on the helmet of Baylor safety Kris Wokomah during the first half of the Bears' game against Auburn on Aug. 29, 2025, in Waco, Texas.
SATURDAY, Sept. 6
Matchup: Baylor (+2.5) at No. 17 SMU
Time/TV: 9 a.m., The CW
Hamm's prediction: Baylor to win outright
Lev’s prediction: Baylor to win outright
Spears’ prediction: SMU to win and cover
Matchup: Iowa (+3.5) at No. 16 Iowa State
Time/TV: 9 a.m., FOX/11
Hamm's prediction: Iowa State to win and cover
Lev’s prediction: Iowa State to win, Iowa to cover
Spears’ prediction: Iowa State to win, Iowa to cover
Matchup: Kansas (+6.5) at Missouri
Kansas players run onto the field before their game against Fresno State Saturday, Aug. 23, 2025, in Lawrence, Kan.
Time/TV: 12:30 p.m., ESPN2
Hamm's prediction: Kansas to win outright
Lev’s prediction: Missouri to win, Kansas to cover
Spears’ prediction: Kansas to win outright
Matchup: West Virginia (-3.5) at Ohio
Time/TV: 1 p.m., ESPNU
Hamm's prediction: West Virginia to win and cover
Lev’s prediction: West Virginia to win and cover
Spears’ prediction: West Virginia to win and cover
Matchup: Army (+17.5) at Kansas State
Time/TV: 4 p.m., ESPN
Hamm's prediction: Kansas State to win, Army to cover
Arizona State wide receiver Jordyn Tyson (0) dives for a first down as he is tackled by Northern Arizona safety Michael Hurst, right, and linebacker Ramere Davis, left, during the first half of their game Saturday, Aug. 30, 2025, in Tempe.
Lev’s prediction: Kansas State to win, Army to cover
Spears’ prediction: Kansas State to win and cover
Matchup: No. 12 Arizona State (-6.5) at Mississippi State
Time/TV: 4:30 p.m., ESPN2
Hamm's prediction: ASU to win, MSU to cover
Lev’s prediction: ASU to win, MSU to cover
Spears’ prediction: MSU to win outright
Matchup: Weber State (+32.5) at Arizona
Time/TV: 7 p.m., ESPN+
Hamm's prediction: Arizona to win and cover
Lev’s prediction: Arizona to win and cover
Spears’ prediction: Arizona to win and cover
BYU quarterback Bear Bachmeier (47) runs the ball during the first half against Portland State, Aug. 30, 2025 in Provo, Utah.
Matchup: Stanford (+18.5) at BYU
Time/TV: 7:15 p.m., ESPN
Hamm's prediction: BYU to win, Stanford to cover
Lev’s prediction: BYU to win and cover
Spears’ prediction: BYU to win and cover
LAST WEEK'S RECORDS
Hamm: 6-2 straight up, 4-4 against the spread
Lev: 7-1 SU, 4-4 ATS
Spears: 6-2 SU, 6-2 ATS
SEASON TO DATE
Hamm: 6-2 SU, 4-4 ATS
Lev: 7-1 SU, 4-4 ATS
Spears: 6-2 SU, 6-2 ATS
