As expected, the Arizona Wildcats are favorites for their Pac-12 home opener against the winless Colorado Buffaloes on Saturday.
Arizona (2-2) is an 18-point favorite against the Buffaloes (0-4), according to Caesar's Sportsbook, which marks the first time the Wildcats are favored to win a conference game since the home game against Oregon State in 2019; UA lost to the Beavers 56-38.
The 18-point spread for Arizona is also the largest for a Pac-12 game since the OSU game in 2017, when the Wildcats were 20-and-a-half-point favorites over the Beavers. It's Arizona's largest spread against Colorado since the Wildcats were 18-and-a-half-point favorites in 2014.
Last season, the Wildcats were shutout 34-0 by Colorado in Boulder.
Colorado-Arizona kicks off at Arizona Stadium at 6:30 p.m. on Pac-12 Network.



