Is this heaven?
No — it's a jam-packed schedule of Big 12 football.
Week 5 kicks off with No. 24 TCU at Arizona State on Friday night and concludes with No. 25 BYU at Colorado on Saturday night. In between, Arizona visits No. 14 Iowa State — the Wildcats' first trip to Ames since 1968.
Our staff prognosticators, Michael Lev and Justin Spears, are back to pick all eight games on this week's slate straight up and against the spread. Lev and Spears are joined this season by Jordan Hamm of Sports360AZ.com.
For more on our predictions — plus an in-depth breakdown of the UA-ISU matchup — check out The Wildcast podcast. It’s available on Apple, Spotify or wherever you get your podcasts.
FRIDAY, Sept. 26
Matchup: No. 24 TCU (+2.5) at Arizona State
Arizona State running back Raleek Brown, left, celebrates his touchdown run against NAU with offensive linemen Jimeto Obigbo (55) and Ben Coleman (62) during the first half Aug. 30, 2025, in Tempe.
Time/TV: 6 p.m., FOX/11
Hamm's prediction: ASU to win and cover
Lev’s prediction: ASU to win and cover
Spears’ prediction: TCU to win outright
Matchup: Houston (-13.5) at Oregon State
Time/TV: 7:30 p.m., ESPN
Hamm's prediction: Houston to win and cover
Lev’s prediction: Houston to win, Oregon State to cover
Spears’ prediction: Houston to win, Oregon State to cover
SATURDAY, Sept. 27
Matchup: Cincinnati (+4.5) at Kansas
Time/TV: 9 a.m., TNT
Hamm's prediction: Cincinnati to win outright
Lev’s prediction: Kansas to win, Cincinnati to cover
Spears’ prediction: Cincinnati to win outright
Matchup: UCF (+6.5) at Kansas State
Time/TV: 9 a.m., FS1
Hamm's prediction: Kansas State to win, UCF to cover
Lev’s prediction: Kansas State to win and cover
Spears’ prediction: Kansas State to win and cover
Matchup: Baylor (-20.5) at Oklahoma State
Time/TV: 12:30 p.m., ESPN2
Hamm's prediction: Baylor to win and cover
Lev’s prediction: Baylor to win and cover
Spears’ prediction: Baylor to win and cover
Matchup: Utah (-13.5) at West Virginia
Time/TV: 12:30 p.m., FOX/11
Hamm's prediction: Utah to win and cover
Lev’s prediction: Utah to win and cover
Spears’ prediction: Utah to win and cover
Arizona quarterback Noah Fifita (1) gestures skyward as he and the Wildcats celebrate his touchdown run in the first quarter vs. Kansas State, Sept. 12, 2025, at Arizona Stadium.
Matchup: Arizona (+6.5) at No. 14 Iowa State
Time/TV: 4 p.m., ESPN
Hamm's prediction: Iowa State to win and cover
Lev’s prediction: Iowa State to win, Arizona to cover
Spears’ prediction: Arizona to win outright
Matchup: No. 25 BYU (-6.5) at Colorado
Time/TV: 7:15 p.m., ESPN
Hamm's prediction: BYU to win and cover
Lev’s prediction: BYU to win and cover
Spears’ prediction: BYU to win and cover
LAST WEEK'S RECORDS
Hamm: 3-5 straight up, 2-6 against the spread
Lev: 3-5 SU, 2-6 ATS
Spears: 6-2 SU, 4-4 ATS
SEASON TO DATE
Hamm: 19-12 SU, 16-15 ATS
Lev: 19-12 SU, 15-16 ATS
Spears: 22-9 SU, 17-14 ATS
